Figure 4

Successfully invading hypervirulent strains of Clostridium difficile (left column, red) competitively exclude pre-existing endemic strains (right column, blue).
The fold increase in infectiousness relative to endemic strains is shown in the top left of the hypervirulent plots. A one-month moving average of the successful hypervirulent strain invasions from 1000 simulated introductions are displayed (with shaded 95% confidence intervals).