Table 1 Epidemiological model symbology and parameterisation.
Symbol | Definition | Value | Ref. |
|---|---|---|---|
βh : β | Transmission coefficient (hypervirulent:endemic strain) MECHANISM 1 | 1–1.5 | Full range tested in simulations |
εh : ε | Develop symptoms (proportion) (hypervirulent:endemic strain); MECHANISM 2 | 1–1.5 | |
α | Hypervirulent strain’s ability to supplant colonized endemic; MECHANISM 3 | 0–1 | |
1-ε | Colonization self-clearance (proportion) | 0.8 | |
η | Develop into asymptomatic but Infectious state (day−1) | 0.2 | |
θ | Develop symptomatic CDI (day−1) | 0.2 | |
ζ | CDI self-resolve (proportion) | 0.33 | |
τ | CDI self-resolve rate (day−1) | 0.5 | |
ρ | CDI treatment (day−1) | 0.1 | |
σ | Treatment failure (proportion) | 0.2 | |
μ | Mortality rate (day−1) | 0.0012 |
