Table 3 Correlation between clinicopathologic features and gefitinib trough concentration

From: The Dissociation of Gefitinib Trough Concentration and Clinical Outcome in NSCLC Patients with EGFR Sensitive Mutations

Characters

r s

P a

EGFR mutation status

0.076

0.485

exon19 deletions

  

exon21 L858R

  

other sensitizing-mutations

  

Gender

−0.102

0.347

Male

  

Female

  

BSA,m2

−0.112

0.320

<1.66

  

≥1.66

  

Age, year

0.077

0.478

<60

  

≥60

  

Smoker

−0.028

0.831

Smoker

  

Non-smoker

  

Staging

−0.065

0.551

Recurrence

  

B or ıV

  

Histology

−0.165

0.127

Adenocarcinoma

  

Non-adenocarcinoma

  

Line

0.174

0.106

First-line setting

  

Later-line setting

  

CNS metastases

−0.142

0.194

CNS metastases

  

Non-CNS metastases

  
  1. *P < 0.05;
  2. aSpearman rank correlation test.