Figure 5
From: MiR-210 inhibits NF-κB signaling pathway by targeting DR6 in osteoarthritis
Effect of miR-210 in OA rats.
(a) The mRNA level of miR-210 in articular cartilages was detected by RT-PCR; (b–d) inflammatory factors in SF samples were measured by ELISA; (e) The expression of DR6, IκBα and p65 in articular cartilages was detected by western blotting; (f) the quantitative data for e. Data are shown as mean ± SD of five rats in each group. NC, normal control group; SS, sham surgery group; OA, OA model group; OA+miR-210, OA model with the treatment of miR-210-expressing lentivirus. Data are shown as mean ± SD of three experimental replicates. *P < 0.05 vs. normal control group; #P < 0.05 vs. sham surgery group; aP < 0.05 vs. OA model group.
