Table 2 Quantification of renal inflammation and fibrosis.

From: Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis

 

F4/80 positive cells

collagen positive area (%)

wt

3.73±1.02

1.47±0.57

ApoE−/−

4.60±1.79

1.06±0.44

wt + WD

3.66±0.86

1.47±0.81

ApoE−/− + WD

4.95±1.76

1.41±0.33

wt + MCD

2.76±0.67

1.48±0.49

ApoE−/− + MCD

13.57±3.08

3.25±1.11

  1. Quantification of F4/80 positive cells as a marker for monocytes/macrophages/dendritic cells and inflammation and collagen positive stained area (%), as a marker of renal fibrosis, showed comparable values in all groups, apart from increased inflammation and fibrosis in ApoE−/− mice fed with MCD diet. Data are presented as mean ± standard deviation.
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