Table 1 Characteristics of case-control studies on microRNA polymorphisms and HNC risk included in the meta-analysis.

From: Significant association between functional microRNA polymorphisms and head and neck cancer susceptibility: a comprehensive meta-analysis

First author	Year	Country/Region	Racial	Source of controls	Case	Control	Genotype distribution						Genotyping methods	Pfor HWE^a	Location
First author	Year	Country/Region	Racial	Source of controls	Case	Control	Case			Control			Genotyping methods	Pfor HWE^a	Location
microRNA-146a rs2910164 G > C
							GG	GC	CC	GG	GC	CC
Jazdzewski	2008	Europe/USA	Caucasian	Healthy	608	901	305	287	16	526	320	55	Applied Biosystems	0.50	Thyroid
Liu	2010	USA	Caucasian	Population	1109	1130	630	411	68	655	405	70	PCR-RFLP	0.49	HN
Chu	2012	China	Asian	Hospital	470	425	54	242	174	54	196	175	PCR-RFLP	0.94	HN
Lung	2013	China	Asian	Healthy	229	3776	24	88	117	497	1807	1472	Applied Biosystems	0.12	NP
Orsós	2013	Hungary	Caucasian	Hospital	468	468	284	168	16	323	136	9	PCR with two-pair primers	0.22	HN
Wei	2013	China	Asian	Population	753	760	136	323	294	138	345	277	MassARRAY iPLEX platform	0.09	Thyroid
Lin	2014	China	Asian	Population	204	440	31	110	63	139	220	81	Applied Biosystems	0.71	Laryngeal
microRNA-196a2 rs11614913 C > T
							CC	CT	TT	CC	CT	TT
Christensen	2010	USA	Caucasian	Population	484	555	182	302^a		188	367^a		Applied Biosystems	NA	HN
Liu	2010	USA	Caucasian	Population	1109	1130	350	565	194	383	545	202	PCR-RFLP	0.74	HN
Chu	2012	China	Asian	Hospital	470	425	57	277	136	87	206	132	PCR-RFLP	0.69	HN
Roy	2014	India	Asian	Hospital	451	448	218	187	46	242	168	38	Applied Biosystems	0.25	Oral
Li	2014	China	Asian	Population	1020	1006	209	489	322	218	518	270	Applied Biosystems	0.30	NP
microRNA-149 rs2292832 C > T
							CC	CT	TT	C/C	CT	TT
Liu	2010	USA	Caucasian	Population	1109	1130	580	441	88	586	445	99	PCR-RFLP	0.27	HN
Chu	2012	China	Asian	Hospital	470	425	37	88	345	26	84	315	Applied Biosystems	< 0.01	HN
Tu	2012	China	Asian	Hospital	273	122	20	129	124	21	52	49	Applied Biosystems	0.27	HN
microRNA-499 rs3746444 A > G
							AA	AG	GG	AA	AG	GG
Liu	2010	USA	Caucasian	Population	1109	1130	745	309	55	710	366	54	PCR-RFLP	0.44	HN
Chu	2012	China	Asian	Hospital	470	425	339	119	12	356	66	3	PCR-RFLP	0.98	HN

MAF: Minor allele frequency in control group.
NP: Nasopharyngeal; HN: head and neck.
Population: Population controls Hospital: Hospital controls Healthy: Healthy controls.
^aHWE in control.

Back to article page

Table 1 Characteristics of case-control studies on microRNA polymorphisms and HNC risk included in the meta-analysis.

Search

Quick links