Table 3 MDR interaction models for schizophrenia.

From: Polymorphisms in MicroRNA Genes And Genes Involving in NMDAR Signaling and Schizophrenia: A Case-Control Study in Chinese Han Population

No. of loci in model

SNPs included in the best combination in each model

Training accuracy

Testing accuracy

CV consistency

OR(95%CI)a

P valueb

1

rs107822

0.5332

0.5086

6/10

1.31(1.09–1.57)

0.0036

2

rs107822, rs890

0.5530

0.5460

9/10

1.78(1.38–3.04)

<0.0001

3

rs107822, rs2306327, rs12342026

0.5712

0.5308

8/10

1.83(1.52–2.20)

<0.0001

4

rs107822,rs2306327,rs890,rs12342026

0.5922

0.5506

10/10

2.35(1.94–2.85)

<0.0001

  1. aOdds ratio represents the odds of schizophrenia in the ‘‘high risk’’ group compared to the ‘‘low risk’’ group identified by MDR.
  2. bP value is corrected by a 1000-fold permutation test.
Back to article page