Figure 3 | Scientific Reports

Figure 3

From: Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides

Figure 3

ssDNA does not dissociate PLN from SERCA.

(a) Fluorescence spectra of SERCA alone and upon addition of ssDNA. (b) FRET of SERCA-PLN complex (cyan) in the absence and presence of ssDNA. Upon addition of ssDNA (purple and green) the FRET signal does not change, indicating no structural changes within the range of the FRET probes. (c) SERCA-PLN FRET at a 10:1 PLN:SERCA ratio (green).

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