Figure 1
From: Upregulation of miR-181s reverses mesenchymal transition by targeting KPNA4 in glioblastoma
miR-181 family was preferentially expressed in proneural glioma.
(A) After annotating the miRNA microarrays according to the TCGA mRNA microarray subtypes, we identified the differentially expressed miRNAs and observed that miR-181 family expression was dominant in the proneural subtype. (B) There was a significant difference in miR-181 family expression among the four TCGA subtypes. miR-181 family expression in the proneural subtype was significantly higher than in the other three subtypes, especially the mesenchymal subtype. (C) When the entire miR-181 family was considered, patients in the miR-181 family low-expression group had a significantly shorter survival time (p = 0.0031).
