Table 2 Cox Hazard Regression Analyses of Clinicopathologic Factors and the miR-181b for Overall Survival in the Independent Cohort (n = 107).
From: Upregulation of miR-181s reverses mesenchymal transition by targeting KPNA4 in glioblastoma
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |
Sex | 0.864 | 0.538–1.386 | 0.544 | |||
Age | 1.047 | 0.650–1.687 | 0.850 | |||
Preoperative KPS score | 0.394 | 0.242–0.641 | <0.001 | 0.516 | 0.304–0.875 | 0.014 |
Extent of resection | 0.491 | 0.292–0.828 | 0.008 | 0.652 | 0.371–1.145 | 0.137 |
IDH1 mutation | 0.399 | 0.216-0.737 | 0.003 | 0.320 | 0.167-0.613 | 0.001 |
MGMT promoter methylation | 1.031 | 0.504-2.108 | 0.933 | |||
miR-181b | 0.287 | 0.172-0.478 | <0.001 | 0.264 | 0.144-0.484 | <0.001 |
