Figure 7

Correlation of plasma lactate, cartilage HIF1α and cytokine levels with the body mass index (BMI) in patients with osteoarthritis.
(a) Correlation of plasma lactate levels with the BMI in human subjects (n = 10). Pearson’s correlations: R = 0.65 and P < 0.05. (b) Correlation of HIF1α protein levels in the cartilages with the BMI in human subjects (n = 10). Pearson’s correlations: R = 0.80 and P < 0.05. (c) Correlation of IL-6 mRNA levels in the cartilages with the BMI in human subjects (n = 10). Pearson’s correlations: R = 0.78 and P < 0.05. (d) Correlation of TNF-α mRNA levels in the cartilages with the BMI in human subjects (n = 10). Pearson’s correlations: R = 0.88 and P < 0.05. (e) Correlation of IL-1β mRNA levels in the cartilages with the BMI in human subjects (n = 10). Pearson’s correlations: R = 0.87 and P < 0.05. (f) Correlation of VEGF mRNA levels in the cartilages with the BMI in human subjects (n = 10). Pearson’s correlations: R = 0.67 and P < 0.05.