Figure 4 | Scientific Reports

Figure 4

From: Curcumin analogues as selective fluorescence imaging probes for brown adipose tissue and monitoring browning

Figure 4

Application of CRANAD-29 for monitoring BAT mass change and BAT activation.

(a) Representative NIR images of control mice (top) and mice after STZ-treatment (bottom). (b) Quantitative analysis of the fluorescence signals in (a). The signal from STZ-induced diabetic mice was significantly lower than that from control mice. (c) Representative NIR images of control mice (top) and mice after cold exposure (bottom). (d) Quantitative analysis of the fluorescence signals in (c). The signal from mice exposed to cold stress was significantly higher than that of control mice, indicating that CRANAD-29 could be used for monitoring BAT activation.

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