Table 2 P. aeruginosa gene transcription under ΔznuA-induced Zn²⁺ depletion.

TonB-dependent receptor (ZnuD)

172.2

0.0012

methyltransferase

15.1

0.00027

TonB-dependent receptor

147.3

cobaltochelatase subunit (CobN)

122.2

ExbD

44.7

hypothetical

56.4

hypothetical

6.5

P-type ATPase importer (HmtA)

5.6

membrane protease subunit of HflC family

14.4

HflC membrane protease subunit

10.6

membrane protease subunit of HflK family

9.0

TonB dependent receptor

8.1

nucleotide binding domain of ABC transporter

8.8

iron periplasmic binding protein

9.1

transmembrane domain of Vitamin B12 ABC permease

8.0

metallo β-lactamase

5.2

—

lysine transporter (LysE)

4.2

—

hypothetical

4.1

hypothetical

5.0

hypothetical

5.0

50S ribosomal protein L36

89.2

0.0013

50S ribosomal protein L31

109.0

Zn²⁺ periplasmic binding protein

45.1

ABC transporter nucleotide binding protein

17.2

lipoprotein release ABC transporter permease

22.1

lipoprotein

10.6

hemolysin III family protein

5.0

—

putative membrane transporter

27.4

hypothetical

35.2

hypothetical

72.9

TonB-dependent siderophore receptor

110.0

hypothetical membrane protein

6.7

0.0014

Zn²⁺ ABC transporter SBP (ZnuA)

5.2

0.0012

cobalamin biosynthesis protein (CobW)

8.9

—

hypothetical

57.5

cobalamin synthesis protein

46.1

Zn²⁺-independent transcription regulator (DksA2)

134.6

glutamine synthetase

6.7

0.00021

N-acetylmuramoyl-L-alanine amidase (AmiA)

18.6

0.00017

GTP cyclohydrolase (FolE2)

93.6

carbonate dehydratase

37.6

dihydroorotase (PyrC2)

37.9

β-lactamase

6.6

—

hypothetical

5.4

—