Figure 2

MicroRNA expression array results:

(A). MicroRNA expression array results of representative 4 tumor-normal paired samples. Significantly differential expression between tumors and adjacent normal samples were found in some of microRNAs (red dots). (B). Scatter plots of promising microRNA that differentially expressed between tumors and normal by array analysis are shown: (a) Average microRNA expression ratios between tumor and adjacent normal tissue of all 8 cases (y axis) are plotted according to the mean expression (x axis). Differentially expressed microRNAs are expected to deviate from the bulk population (red dots). (b) Sub-group analyses scatter plot of mean tumor expression levels (y axis) and adjacent normal expression levels (x axis) of individual microRNAs for 3 Adenocarcinoma cases and (c) same for 5 squamous cell carcinoma cases. Probes with a large differential expression are identified as red dots.