Figure 8

Tau fibrilization assay.
In vitro assay showing Tau 244–372 aggregation induced by mCRP (10 μg/ml; 24 h) (c), with a similar profile to that produced by the positive control arachidonic acid (150 μM). (a) shows the control Tau incubated with all other buffer component’s minus CRP or arachidonic acid (b). These experiments were carried out at least twice and a representative example is shown. Magnification bars10 mm = 1 μM.