Figure 3

(a) Effect of S. crispus on regulation of PCNA protein in the colon tissue of rats (A) Normal group with normal crypts, (B) AOM group, (C) 5-FU group, (D) S. crispus 250 mg/kg plant treated group, (E) S. crispus 500 mg/kg plant treated group (100× magnification). Arrow indicates cells with PCN protein. (Immunohistochemical stain, PCNA stain). (b) Effect of S. crispus on % regulation of PCNA protein in AOM-induced rats’ colon tissue.