Table 4 Effects of S. crispus extracts on the number of crypts per focus in AOM induced ACF in colons of male rats.

From: Chemopreventive effects of Strobilanthes crispus leaf extract on azoxymethane-induced aberrant crypt foci in rat colon

Group

Number of foci containing

1 crypt

2 crypts

3 crypts

4 crypts

>5 crypts

Cancer control group (AOM)

26 ± 7.15

36 ± 8.4

31 ± 4.4

25 ± 1.4

32 ± 7.3

AOM + 5-FU

10 ± 2.1**

9 ± 2.3**

9 ± 2.6**

5 ± 1.5**

8 ± 2.6**

AOM + S. crispus (250 mg/kg)

4 ± 1.4**

11 ± 2.3**

13 ± 0.5**

8 ± 2.5**

8 ± 2.4**

AOM + S. crispus (500 mg/kg)

8 ± 0.5**

10 ± 2.7**

11 ± 2.1**

8 ± 1.2**

6 ± 1.2**

  1. All values are in mean ± S.E.M. **Significant difference at p < 0.01 (ANOVA, Tukey’s post hoc). 5-FU: 5-Fluorouracil; ACF: aberrant crypt foci; AOM: azoxymethane.
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