Table 1 Clinical characteristics of patients with primary liver cancer n (%).

From: Overexpression Of Hepatocyte Nuclear Factor-1beta Predicting Poor Prognosis Is Associated With Biliary Phenotype In Patients With Hepatocellular Carcinoma

Variable

Cohort1

Cohort2

P value

(HCC, n = 183)

(ICC, n = 69)

Age

49.6 ± 11.0

56.5 ± 11.8

0.193

Gender (male/female)

162/21

49/20

0.001*

Tumor number (multiple)

24 (13.1)

12 (17.4)

0.387

Maximum tumor diameter

5.2 ± 2.6

6.6 ± 3.2

0.688

Lymphovascular invasion

117 (63.9)

27 (39.1)

0.001*

Macrovascular invasion

12 (6.6)

10 (14.5)

0.047*

Cirrhosis

58 (31.7)

21(30.4)

0.848

HBsAg (positive)

172(94.0)

37(53.6)

0.001*

Histological grade

   

Well/moderately

133(72.7)

56(81.2)

0.166*

Poorly

50(27.3)

13(18.8)

 

AFP (ng/mL)

399.2(1.7-1000.0)

6.7(1.2-1000.0)

0.001*

CEA (ng/mL)

4.1(0.0-58.2)

4.2(0.0-51.3)

0.698

CA19-9 (U/mL)

13.4(0.0-665.0)

40.0(6.0-725.0)

0.001*

ALT (U/L)

53.2(9.8-247.0)

51.2(16.0-238.0)

0.521

AST (IU/L)

  1. AFP, alpha-fetoprotein; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19–9; ALT, alanine aminotransferase; AST, aspartate aminotransferase; *P < 0.05 was considered statistically significant.
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