Table 2 Hypermutated tumors (T.sns > 60/Mb) and tumors with discordant MSI status between NGSclassifier and laboratory tests.
From: MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations
Sample ID | Training set? | S.ind | MSI-H by laboratory test? | MSI-H by MSIseq? | POLE-like Mutation signature? | Mutation in POLEa |
|---|---|---|---|---|---|---|
Hypermutated tumors with concordant MSI status | ||||||
TCGA-F5-6814 | Y | 0.045 | N | N | Y | None |
TCGA-CA-6717 | Y | 0.11 | N | N | Y | Exo |
TCGA-AZ-4315 | Y | 0.045 | N | N | Y | Other |
TCGA-EI-6917 | Y | 0.091 | N | N | Y | Exo |
TCGA-AA-3510 | N | 0.023 | N | N | Y | Other |
TCGA-CA-6718 | Y | 0.023 | N | N | Y | Exo |
Hypermutated tumors with discordant MSI status | ||||||
TCGA-AM-5821 | Y | 0.25 | Y | N | N | None |
TCGA-AM-5820 | N | 2.61 | N | Y | N | None |
Other tumors with discordant MSI status | ||||||
TCGA-A5-A0GD | Y | 0.00 | Y | N | N | None |
TCGA-DC-6154 | Y | 0.045 | Y | N | N | None |
TCGA-G4-6304 | N | 0.27 | Y | N | N | None |
