Table 3 Fisher test for non-silent mutations in the POLE gene. “POLE signature” refers to very high rates of TCT > TAT and TCG > TTG mutations (Supplementary Figure 1).
From: MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations
POLE signature? | |||
|---|---|---|---|
Y | N | ||
Non-silent mutation in POLE? | Y | 5 | 20 |
N | 1 | 500 | |