Table 3 Fisher test for non-silent mutations in the POLE gene. “POLE signature” refers to very high rates of TCT > TAT and TCG > TTG mutations (Supplementary Figure 1).

From: MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations

  

POLE signature?

Y

N

Non-silent mutation in POLE?

Y

5

20

N

1

500