Figure 3
From: Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype
KRASG12V-induced tumors exhibit SDC-like phenotypes.
(A–E) H&E staining of submandibular glands harvested from LGL-KRasG12V;Ela-CreERT mice at indicated time points revealed gradual abnormal manifestations starting from day-9 post TAM-feeding. Scale bars: 20 μm and100 μm (inset). G: GCT; A: acini; S: sarcomatous element; SD: striated duct; ED: excretory duct.
