Figure 3 | Scientific Reports

Figure 3

From: Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease

Figure 3

Validation of M(IFNγ + LPS, TNFα) and M(IL-4, IL-13) signatures under controlled clinical settings.

(A) M(IFNγ + LPS, TNFα) signature response of alveolar macrophages after LPS instillation in the lung based on Gene Set Enrichment Analysis (GSEA) (left) and topological representation (landscape analysis) (right). (B) M(IL-4, IL-13) signature response of bronchial biopsy from asthmatic patients based on GSEA (left) and landscape analysis (right).

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