Figure 4
From: Non-immune immunoglobulins shield Schistosoma japonicum from host immunorecognition
Hierarchical clustering of the expression profiles of the S. japonicum immunoglobulin-binding proteins during four developmental stages.
The heat-map of 200 genes encoding for the potential Ig-binding proteins extracted from the microarray dataset (E, eggs; C, cercariae; S, hepatic schistosomula; P, paired adult worms). Most of the genes were up-regulated in the cercariae, schistosomula or adult worms. Genes in the red box represent a cluster of genes abundantly expressed both in the schistosomula and adult worms while the schistosome lives in the definitive host. The color scale represents the relative expression levels, with yellow indicating an up-regulated gene, blue a down-regulated gene and black a gene with unchanged expression.
