Table 1 Correlations between serum bile acids concentration and FGF19.

From: Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease

Bile acid species

Correlation coefficient (r)

p value

UDCA

0.146

0.30

GUDCA

0.586

<0.0001

TUDCA

0.749

<0.0001

LCA

−0.055

0.70

GLCA

−0.111

0.44

TLCA

−0.030

0.83

LCA-S

0.062

0.66

LCA-3G

0.493

0.0002

LCA-24G

-0.152

0.27

CA

0.041

0.77

GCA

0.679

<0.0001

TCA

0.311

0.03

CA-24G

0.017

0.90

CDCA

0.024

0.46

DCA-3G

−0.027

0.85

DCA-24G

−0.143

0.32

GCDCA

0.674

<0.0001

TCDCA

0.370

0.008

CDCA-3G

0.442

0.001

CDCA-24G

0.049

0.73

DCA

−0.064

0.66

GDCA

0.061

0.67

TDCA

0.031

0.83

HDCA

−0.105

0.46

HDCA-6G

−0.084

0.56

HDCA-24G

0.116

0.42

HCA

0.031

0.83

HCA-6G

−0.064

0.66

HCA-24G

−0.064

0.65

Total bile acids

0.663

<0.0001

  1. Abbreviations: UDCA, GUDCA, TUDCA – Ursodeoxycholic acid and its glycine and taurine conjugates, respectively; LCA, GLCA, TLCA, LCA-3G, LCA-24G – lithocholic acid and its glycine, taurine, 3-O-glucoronide and 24-O-glucuronide conjugates, respectively; LCA-S – sulpholithocholate, CA, GCA, TCA, CA-24G – cholic acid and its glycine, taurine and 24-O-glucuronide conjugates, respectively; CDCA, GDCA, TGCDA, CDCA-3G, CDCA-24G – chenodeoxycholic acid and its glycine, taurine, 3-O-glucoronide and 24-O-glucuronide conjugates, respectively; DCA, GDCA, TDCA, DCA-3G, DCA-24G – deoxycholic acid and its glycine, taurine, 3-O-glucuronide and 24-O-glucuronide conjugates, respectively; HDCA, HDCA-6G, HDCA-24G – hyodeoxycholic acid and its 6-O-glucuronide and 24-O-glucuronide conjugates, HCA, HCA-6G, HCA-24G – hyocholic acid and its 6-O-glucuronide and 24-O-glucuronide conjugates.
Back to article page