Figure 2 | Scientific Reports

Figure 2

From: Enhancing flavonoid production by systematically tuning the central metabolic pathways based on a CRISPR interference system in Escherichia coli

Figure 2

Screening genetic targets to redirect the carbon flux toward malonyl-CoA.

Genes selected for efficient channeling of the carbon flux toward malonyl-CoA are shown in red. The metabolic pathway that performs heterologous biosynthesis of (2S)-naringenin from L-tyrosine in E. coli is shown in blue. CHI: chalcone isomerase; CHS: chalcone synthase; 4CL: 4-coumarate:CoA ligase; E4P: erythrose-4-phosphate; PEP: phosphoenolpyruvate; TAL: tyrosine ammonia lyase.

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