Table 4 Association between IREB2 rs2568494 and FAM13A rs2869967 SNPs with lung function measures and smoking exposure in the COPD and LC.

From: Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases

  

Genotype

Lung function measures

Pack-years of smoking

FEV1 [% pred.]

FEV1/VC [%]

LC

IREB2

GG

84

92

44.2

 

rs2568494

GA

82

92

46.6

  

AA

85

91

43.5

  

P

0.364

0.94

0.408

   

FEV1 [% pred.]

FEV1/FVC [%]

 

COPD

FAM13A

TT

43

56

47.3

 

rs2869967

CT

40.7

52.3

39.8

  

CC

41.4

53.7

45.1

  

P

0.816

0.335

0.454

  1. LC—lung cancer; COPD—chronic obstructive pulmonary disease; FEV1—forced expiratory volume in 1 second; VC—vital capacity; FVC—forced vital capacity; FEV1/VC, FEV1/FVC—ratio; % pred.—% of predicted value; P(One-way ANOVA—Ordinary test).