Figure 5

(a) Steady-state concentration profiles for domains under a critical length (h<h_c) and β = 0. The inset shows a corresponding space-time plot of the total myosin concentration. The concentrations of the stalled, processive and free motors (m_b, m_w, m_f) are denoted by the red, blue and green lines respectively and the sum total concentration in black. The horizontal dashed red line denotes the concentration of stalled myosins in the M^U state. Parameters used are: v_w = 0.6 μm/sec, v_b = 0.016 μm/sec, D = 0.1 μm²/sec, D_b = 0.0001 μm²/sec, sec⁻¹, sec⁻¹, sec⁻¹, sec⁻¹, sec⁻¹, sec⁻¹, k_bw = 2 μm² and  μm⁻¹. (b) Snapshots of dynamics on large domains h > h_c in which pulses form and propagate towards the protrusion base. The pulses are generated periodically. (c) Overlayed time course (at 30 sec intervals) of a single pulse (solid line) that forms and decays as it propagates (dashed-dot and dashed pulses are from the previous and next cycles respectively). (d) Pulse train in a longer protrusion.