Figure 5

NMR structure of S. Typhimurium Crl.
(a) Backbone ensemble structure of CrlSTM showing the 10 final low-energy conformers with the lowest CYANA target function in cartoon representation. Secondary structure elements are annotated using the numbering of CrlPM18. The two views are rotated by 180°. (b) The electrostatic surface potential was calculated with Delphi44 using the conformer 1. Colours are red to blue for acidic to basic potential. Critical residues, including D36, which delineate the entrance of the cavity, are indicated.