Table 2 Table summarising the associations in the ADR group between abnormal glomeruli (5w) and the four biomarkers: albuminuria at the maximum observed and at four weeks, FITC-Sinistrin half-life, IRDye clearance half-life, IRDye TMAX delay.

From: Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy

Biomarker

Coef. estimate

SE

P-value

AlbuminuriaMAX (mg/24 h)

0.04

0.05

0.45

Albuminuria4w (mg/24 h)

0.2

0.15

0.21

FITC-sinistrin half-life4w (min)

0.94

0.18

0.001

IRDye clearance half-life (s)

0.12

0.04

0.02

IRDye TMAX delay (s)

0.16

0.03

0.002

  1. The results included in this table were derived from the statistical models described in Table S5 by using contrast analysis. Each coefficient estimate indicates the change in percentage of abnormal glomeruli per unit change of the corresponding biomarker.
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