Figure 1 | Scientific Reports

Figure 1

From: Changes in Gene Expression Patterns of Circadian-Clock, Transient Receptor Potential Vanilloid-1 and Nerve Growth Factor in Inflamed Human Esophagus

Figure 1

Analytical data of the expression of circadian-clock genes, (A) PER1 (period1), (B) PER2, (C) PER3, (D) TIM (timeless), (E) BMAL1 (brain and muscle aryl-hydrocarbon receptor nuclear translocator-like protein-1), (F) CLOCK (circadian locomotor output cycles kaput), (G) CRY1 (cryptochrome 1) and (H) CRY2 in the esophagus of patient controls (PC) and the patients with different Los Angeles (LA) classification grades (A–D) of gastroesophageal reflux disease.

The biopsies from all subjects were divided between 9 AM and 4 PM time points and referred to as the AM and PM groups. **p < 0.01; ***p < 0.001 compared with the same groups in the other biopsy time point; #p < 0.05; ##p < 0.01; ###p < 0.001 compared with the other groups in the same biopsy time point. Line represents the mean value.

Back to article page