Table 3 Odds ratio (95% CIs) of cervical cancer for quartiles of serum antioxidant vitamin concentrations in Chinese women.

From: Associations between antioxidant vitamins and the risk of invasive cervical cancer in Chinese women: A case-control study

 

Quartiles of serum antioxidant vitamin concentrations

P-trend

Q1

Q2

Q3

Q4

Serum retinol

 N (case/control)

134/185

116/186

103/186

105/185

 

 Median (case/control), μg/da

25.7/25.6

46.7/46.8

75.1/75.5

92.0/92.8

 

 Crude ORs (95% CI)

1.00

0.86 (0.62, 1.19)

0.77 (0.55, 1.06)

0.78 (0.57, 1.09)

0.102

 Adjusted ORs (95% CI)

1.00

0.87 (0.63, 1.20)

0.79 (0.57, 1.10)

0.85 (0.61, 1.19)

0.258

Serum α-carotene

 N (case/control)

130/185

131/186

117/186

80/185

 

 Median (case/control), mg/da

3.06/3.06

4.52/4.56

5.94/5.99

6.43/6.51

 

 Crude ORs (95% CI)

1.00

1.00 (0.73, 1.38)

0.90 (0.65, 1.24)

0.62 (0.44, 0.87)

0.006

 Adjusted ORs (95% CI)

1.00

1.01 (0.73, 1.38)

0.93 (0.67, 1.29)

0.66 (0.46, 0.93)

0.024

Serum β-carotene

 N (case/control)

155/185

120/186

92/186

87/185

 

 Median (case/control), mg/da

9.6/9.5

16.1/16.1

24.0/24.8

33.2/33.6

 

 Crude ORs (95% CI)

1.00

0.77 (0.56, 1.05)

0.59 (0.43, 0.82)

0.61 (0.44, 0.85)

0.001

 Adjusted ORs (95% CI)

1.00

0.79 (0.57, 1.08)

0.62 (0.44, 0.87)

0.63 (0.45, 0.90)

0.006

Serum vitamin E

 N (case/control)

167/185

107/186

100/186

83/185

 

 Median (case/control), μg/da

0.36/0.35

0.82/0.89

1.29/1.32

1.56/1.58

 

 Crude ORs (95% CI)

1.00

0.64 (0.46, 0.88)

0.60 (0.43, 0.82)

0.50 (0.36, 0.70)

<0.001

 Adjusted ORs (95% CI)

1.00

0.65 (0.47, 0.90)

0.61 (0.44, 0.84)

0.53 (0.37, 0.74)

<0.001

Serum vitamin C

 N (case/control)

167/185

118/186

100/186

72/185

 

 Median (case/control), g/da

492/495

796/799

1280/1286

1575/1600

 

 Crude ORs (95% CI)

1.00

0.70 (0.52, 0.96)

0.60 (0.43, 0.82)

0.46 (0.32, 0.64)

<0.001

 Adjusted ORs (95% CI)

1.00

0.72 (0.53, 0.99)

0.61 (0.44, 0.85)

0.48 (0.33, 0.69)

<0.001

  1. Crude and adjusted ORs (95% CI): from unconditional logistic regression models. Covariates include age, body mass index (BMI), marital status, education, family history of cancers, HPV infection, passive smoking, current alcohol drinking, calcium supplement use, multivitamin use, menopause, oral contraceptive use, estrogen use, physical activity and daily energy intake (log-transformed).
  2. aMedian percentage of total energy in cases and controls.
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