Table 3 Comparative genomic analysis of the outbreak strains with the reference strains and the local strain CDC228§.
Region | Location | Gene | Nucleotide Change (amino acid substitution) | ||
|---|---|---|---|---|---|
DG01_2011 | CDC228 | Outbreak strains | |||
ITR | 518 | inverted terminal repeat | Insertion of T | — | — |
E1A | 815 | 28 kDa protein | — | — | T→G (W→L) |
1444 | — | — | A→G | ||
IVa2 | 4133 | — | — | — | C→T |
E2B | 5517 | DNA polymerase | G→C (D→E) | — | — |
7494 | — | — | G→T (L→I) | ||
9168 | preterminal DNA-binding protein | — | — | C→T& | |
9327 | — | — | G→T& | ||
L1 | 10698–10709 | Virus-associated RNA II | — | — | Deletion of GTTGCGGTGTGC |
10734 | — | — | G→A | ||
10816 | — | Insertion of T | Insertion of T | ||
10830 | G→A | — | — | ||
L2 | 14594 | Penton | T→C (V→A) | — | — |
14854 | — | — | A→G (N→D) | ||
L3 | 17871 | Protein VI precursor | — | — | C→G (P→A) |
L4 | 24298 | hexon-assembly associated protein | C→T& | — | — |
24904 | — | — | T→C& | ||
E3 | 27799 | 16.1 kDa protein | — | — | C→T (P→S) |
Non-coding Region | 29950 | — | — | — | Insertion of T |
E4 | 32450 | E4 | — | — | T→C (N→D) |
33155 | 32 kDa protein | G→T (P→Q) | — | — | |
Non-coding Region | 34904 | — | — | — | G→A |
ITR | 35125 | inverted terminal repeat | — | — | C→A |
