Table 4 The HRs of incident HU across the quartiles of Hct in male population.
Quartile of baseline Hct | P for trend | ||||
|---|---|---|---|---|---|
1(lowest) | 2 | 3 | 4(highest) | ||
Minimum follow-up = 1 year (33110 person-years) | |||||
Median (range) | 39.8(<41.4) | 42.5(41.4–43.5) | 44.5(43.6–45.5) | 46.9(>45.5) | – |
No. of subjects | 3669 | 3713 | 3461 | 3579 | – |
Person-years of follow-up | 9422.5 | 8881.5 | 7727.5 | 7078.5 | – |
Incidence of HU (per 1000 person-years) | 55.2 | 56.1 | 63.9 | 78.5 | – |
Unadjusted HR (95%CI) | 1.00(reference) | 1.01(0.89, 1.14) | 1.13(1.00, 1.28) | 1.36(1.21, 1.54) | 0.00 |
P value | – | 0.93 | 0.05 | 0.00 | |
Age, BMI adjusted HR (95%CI) | 1.00(reference) | 0.95(0.84, 1.08) | 1.04(0.92, 1.18) | 1.22(1.08, 1.38) | 0.00 |
P value | – | 0.43 | 0.57 | 0.00 | – |
Multivariable adjusted HR (95%CI) | 1.00(reference) | 0.92(0.81, 1.04) | 0.96(0.85, 1.10) | 1.11(0.98, 1.26) | 0.09 |
P value | – | 0.17 | 0.57 | 0.11 | – |
Minimum follow-up = 2 years (31814 person-years) | |||||
Multivariable adjusted HR (95%CI) | 1.00(reference) | 0.90(0.79, 1.02) | 0.98(0.86, 1.11) | 1.13(0.99, 1.28) | 0.04 |
P value | 0.10 | 0.71 | 0.07 | ||
Minimum follow-up = 3 years (26441 person-years) | |||||
Multivariable adjusted HR (95%CI) | 1.00(reference) | 0.87(0.77, 0.99) | 0.96(0.88, 1.13) | 1.15(1.02, 1.31) | 0.01 |
P value | – | 0.04 | 0.96 | 0.03 | |
Minimum follow-up = 4 years (20756 person-years) | |||||
Multivariable adjusted HR (95%CI) | 1.00(reference) | 0.94(0.83, 1.08) | 1.09(0.95, 1.24) | 1.40(1.23, 1.59) | 0.00 |
P value | – | 0.40 | 0.22 | 0.00 | – |
