Table 5 The HRs of incident HU across the quartiles of Hct in female population.
Quartile of baseline Hct | P for trend | ||||
|---|---|---|---|---|---|
1(lowest) | 2 | 3 | 4(highest) | ||
Minimum follow-up = 1 year (29787 person-years) | |||||
Median (range) | 34.3(<35.7) | 36.6(35.7–37.5) | 38.4(37.6–39.3) | 40.5(>39.3) | – |
No. of subjects | 3401 | 3276 | 3276 | 3165 | – |
Person-years of follow-up | 8359.5 | 7700 | 7248 | 6479.5 | – |
Incidence of HU (per 1000 person-years) | 18.9 | 18.7 | 23.2 | 31.9 | – |
Unadjusted HR (95%CI) | 1.00(reference) | 0.99(0.79, 1.24) | 1.23(0.99, 1.53) | 1.70(1.38, 2.09) | 0.00 |
P value | 0.92 | 0.06 | 0.00 | ||
Age, sex, BMI adjusted HR (95%CI) | 1.00(reference) | 1.00(0.80, 1.26) | 1.20(0.96, 1.49) | 1.51(1.23, 1.86) | 0.00 |
P value | – | 0.98 | 0.11 | 0.00 | – |
Multivariable adjusted HR (95%CI) | 1.00(reference) | 0.94(0.75, 1.18) | 1.08(0.87, 1.35) | 1.26(1.01, 1.56) | 0.02 |
P value | – | 0.58 | 0.48 | 0.04 | – |
Minimum follow-up = 2 years (28603.5 person-years) | |||||
Multivariable adjusted HR (95%CI) | 1.00(reference) | 0.92(0.73, 1.16) | 1.09(0.88, 1.36) | 1.25(1.01, 1.55) | 0.02 |
P value | – | 0.50 | 0.42 | 0.04 | |
Minimum follow-up = 3 years (22377 person-years) | |||||
Multivariable adjusted HR (95%CI) | 1.00(reference) | 0.97(0.77, 1.23) | 1.10(0.87, 1.38) | 1.35(1.08, 1.68) | 0.00 |
P value | – | 0.83 | 0.44 | 0.01 | |
Minimum follow-up = 4 years (16622 person-years) | |||||
Multivariable adjusted HR (95%CI) | 1.00(reference) | 1.02(0.80, 1.31) | 1.33(1.05, 1.67) | 1.61(1.29, 2.02) | 0.00 |
P value | – | 0.88 | 0.02 | 0.00 | |
