Table 2 The top 15 new interactions predicted by RLS-KP with the eigenvalue transformation applied.
From: An eigenvalue transformation technique for predicting drug-target interaction
Rank | Drug ID | New drug-target interactions | Target name | |
|---|---|---|---|---|
Drug name | Target ID | |||
1 | DB01544 | Flunitrazepam | P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 |
2 | DB01567 | Fludiazepam | Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 |
3 | DB00546 | Adinazolam | Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 |
4 | DB01567 | Fludiazepam | P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 |
5 | DB00546 | Adinazolam | P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 |
6 | DB01567 | Fludiazepam | Q9UN88 | Gamma-aminobutyric acid receptor subunit theta |
7 | DB01394 | Colchicine | P68371 | Tubulin beta-4B chain |
8 | DB00334 | Olanzapine | P30939 | 5-hydroxytryptamine receptor 1F |
9 | DB00546 | Adinazolam | Q9UN88 | Gamma-aminobutyric acid receptor subunit theta |
10 | DB00408 | Loxapine | P30939 | 5-hydroxytryptamine receptor 1F |
11 | DB00909 | Zonisamide | Q9UQD0 | Sodium channel protein type 8 subunit alpha |
12 | DB01586 | Ursodeoxycholic acid | Q04828 | Aldo-keto reductase family 1 member C1 |
13 | DB00936 | Salicyclic acid | P52895 | Aldo-keto reductase family 1 member C2 |
14 | DB08901 | Ponatinib | A9UF02 | Non-specific protein-tyrosine kinase |
15 | DB06772 | Cabazitaxel | Q71U36 | Tubulin alpha-1A chain |
