Table 2 SIRs for type 2 diabetes mellitus after a specified autoimmune disease by gender.
From: Subsequent Type 2 Diabetes in Patients with Autoimmune Disease
Autoimmune disease | All | Male | Female | ||||||
---|---|---|---|---|---|---|---|---|---|
O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | |
Addison disease | 108 | 2.63 | 2.16–3.18 | 38 | 2.04 | 1.44–2.80 | 70 | 3.14 | 2.44–3.96 |
Amyotrophic lateral sclerosis | 43 | 0.84 | 0.61–1.14 | 29 | 0.83 | 0.56–1.20 | 14 | 0.87 | 0.47–1.46 |
Ankylosing spondylitis | 314 | 1.32 | 1.17–1.47 | 223 | 1.23 | 1.08–1.40 | 91 | 1.58 | 1.27–1.94 |
Autoimmune hemolytic anemia | 21 | 1.77 | 1.09–2.71 | 12 | 2.04 | 1.05–3.58 | 9 | 1.51 | 0.68–2.87 |
Behcet disease | 81 | 1.24 | 0.98–1.54 | 58 | 1.18 | 0.89–1.52 | 23 | 1.41 | 0.90–2.13 |
Celiac disease | 251 | 1.10 | 0.96–1.24 | 134 | 1.22 | 1.02–1.44 | 117 | 0.98 | 0.81–1.18 |
Chorea minor | 10 | 8.00 | 3.81–14.77 | 4 | 8.34 | 2.17–21.56 | 6 | 7.79 | 2.80–17.07 |
Chronic rheumatic heart disease | 476 | 1.66 | 1.51–1.82 | 229 | 1.44 | 1.26–1.64 | 247 | 1.94 | 1.70–2.20 |
Crohn disease | 713 | 1.54 | 1.43–1.66 | 407 | 1.51 | 1.37–1.67 | 306 | 1.58 | 1.41–1.77 |
Discoid lupus erythematosus | 60 | 1.09 | 0.83–1.41 | 22 | 1.15 | 0.72–1.74 | 38 | 1.06 | 0.75–1.46 |
Graves/hyperthyroidism | 1772 | 1.47 | 1.41–1.54 | 410 | 1.49 | 1.35–1.64 | 1362 | 1.47 | 1.39–1.55 |
Hashimoto/hypothyroidism | 2013 | 2.01 | 1.92–2.10 | 430 | 2.09 | 1.89–2.29 | 1583 | 1.99 | 1.89–2.09 |
Immune thrombocytopenic purpura | 182 | 2.46 | 2.12–2.85 | 97 | 2.42 | 1.96–2.96 | 85 | 2.51 | 2.00–3.10 |
Localized scleroderma | 75 | 1.72 | 1.35–2.15 | 22 | 1.90 | 1.19–2.88 | 53 | 1.65 | 1.24–2.16 |
Lupoid hepatitis | 68 | 5.75 | 4.46–7.29 | 23 | 5.41 | 3.42–8.13 | 45 | 5.94 | 4.33–7.95 |
Multiple sclerosis | 303 | 1.22 | 1.09–1.37 | 120 | 1.12 | 0.92–1.33 | 183 | 1.30 | 1.12–1.51 |
Myasthenia gravis | 92 | 1.68 | 1.36–2.06 | 53 | 1.79 | 1.34–2.34 | 39 | 1.56 | 1.11–2.13 |
Pernicious anemia | 140 | 1.21 | 1.01–1.42 | 86 | 1.39 | 1.11–1.72 | 54 | 0.99 | 0.75–1.30 |
Polyarteritis nodosa | 52 | 2.01 | 1.50–2.64 | 30 | 2.21 | 1.49–3.16 | 22 | 1.79 | 1.12–2.71 |
Polymyalgia rheumatica | 1900 | 1.82 | 1.74–1.91 | 724 | 1.68 | 1.56–1.81 | 1176 | 1.92 | 1.81–2.03 |
Polymyositis/dermatomyositis | 94 | 2.10 | 1.70–2.58 | 51 | 2.32 | 1.73–3.05 | 43 | 1.90 | 1.37–2.56 |
Primary biliary cirrhosis | 96 | 2.18 | 1.77–2.66 | 26 | 2.63 | 1.72–3.86 | 70 | 2.05 | 1.60–2.59 |
Psoriasis | 3028 | 2.03 | 1.96–2.10 | 1579 | 1.88 | 1.78–1.97 | 1449 | 2.22 | 2.11–2.34 |
Reiter disease | 14 | 1.20 | 0.65–2.02 | 12 | 1.17 | 0.60–2.06 | 2 | 1.40 | 0.13–5.14 |
Rheumatic fever | 118 | 1.32 | 1.09–1.58 | 84 | 1.20 | 0.96–1.49 | 34 | 1.77 | 1.22–2.47 |
Rheumatoid arthritis | 2070 | 1.50 | 1.44–1.57 | 788 | 1.52 | 1.42–1.63 | 1282 | 1.49 | 1.41–1.57 |
Sarcoidosis | 646 | 2.11 | 1.95–2.28 | 346 | 2.02 | 1.81–2.24 | 300 | 2.24 | 1.99–2.51 |
Sjögren syndrome | 353 | 1.52 | 1.37–1.69 | 65 | 1.67 | 1.29–2.12 | 288 | 1.50 | 1.33–1.68 |
Systemic lupus erythematosus | 201 | 1.83 | 1.59–2.10 | 44 | 1.50 | 1.09–2.02 | 157 | 1.95 | 1.66–2.28 |
Systemic sclerosis | 129 | 1.34 | 1.12–1.60 | 71 | 1.44 | 1.13–1.82 | 58 | 1.24 | 0.94–1.61 |
Ulcerative colitis | 1359 | 1.73 | 1.64–1.82 | 875 | 1.77 | 1.66–1.89 | 484 | 1.65 | 1.51–1.81 |
Wegener granulomatosis | 215 | 1.45 | 1.26–1.66 | 80 | 1.44 | 1.14–1.79 | 135 | 1.46 | 1.22–1.73 |
All | 15103 | 1.66 | 1.63–1.68 | 6519 | 1.62 | 1.58–1.66 | 8584 | 1.68 | 1.65–1.72 |