Table 2 Estimates of the variance explained by individual TGCT risk SNPs.
SNP | Odds Ratio | Locus | Gene(s) | Fraction of Variance Explained |
|---|---|---|---|---|
rs2072499 | 1.19 | 1q22 | non-coding | 0.0030 ± 0.0211 |
rs3790672 | 1.20 | 1q24.1 | non-coding | 0.0013 ± 0.0211 |
rs10510452 | 1.24 | 3p24.3 | DAZL | 0.0029 ± 0.0197 |
rs1510272 | 1.16 | 3q25 | SSR3/TIPARP | 0.0048 ± 0.0197 |
rs17021463 | 1.15 | 4q22.2 | HPGDS | 0.0035 ± 0.0182 |
rs2720460 | 1.24 | 4q24 | CENPE | 0.0046 ± 0.0181 |
rs4635969 | 1.54 | 5p15 | TERT | 0.0001 ± 0.0171 |
rs4624820 | 1.37 | 5q31 | SPRY4 | 0.0017 ± 0.0172 |
rs3805663 | 1.25 | 5q31.1 | CATSPER3/PITX1 | 0.0001 ± 0.0172 |
rs210138 | 1.50 | 6p21 | BAK1 | 0.0108 ± 0.0178 |
rs12699477 | 1.16 | 7p22.3 | MAD1L1 | 0.0049 ± 0.0162 |
rs7010162 | 1.22 | 8q13.3 | PRDM14 | 0.0012 ± 0.0157 |
rs755383 | 1.37 | 9p24 | DMRT1 | 0.0144 ± 0.0159 |
rs995030 | 2.55 | 12q21 | KITLG | 0.0177 ± 0.0163 |
rs2900333 | 1.27 | 12p13 | ATF7IP | 0.0028 ± 0.0167 |
rs8046148 | 1.32 | 16q12.1 | HEATR3 | 0.0044 ± 0.0136 |
rs4888265 | 1.20 | 16q22.3 | RFWD3 | 0.0013 ± 0.0136 |
rs9905704 | 1.21 | 17q22 | RAD51C/TEX14 | 0.0095 ± 0.0104 |
rs2839243 | 1.26 | 21q22.3 | non-coding | 0.0033 ± 0.0090 |
Total | 0.0921 ± 0.0735 |
