Figure 12

DGLHD decreased JAK2, STAT3 protein expression and increased SOCS3 level in the pancreas, spleen and thymus.
(A) Respectively western blot results showed the expressions of JAK2, STAT3, p-STAT3 and SOCS3 in 12 week-old NOD mice treated with DGLHD for 4 weeks from 8 until 12 weeks and model control group. β-actin was used as loading control. (B) Bar graphs showed semi-quantitative evaluation of their expression by densitometry. Data were presented as means ± SD (n = 3). *P < 0.05, **P < 0.01 compared with model control group.