Figure 4

DGLHD or active ingredients functioned as pancreas islet β cells repairing.
(A) Effect of DGLHD on the expression of AAT-1 in NOD mice serum and DCs supernatant (n = 6). (B) Effect of DGLHD on the expression of CyclinD1, Bcl-2, Bax mRNA and Bcl-2/Bax in the pancreas, spleen and thymus of NOD mice (n = 3). (C) Effect of DGLHD and active ingredients on the expression of CyclinD1, Bcl-2, Bax mRNA and Bcl-2/Bax in NIT-1 cell line (n = 3). Data were presented as means ± SD. *P < 0.05, **P < 0.01 compared with model control/control group. #P < 0.05, ##P < 0.01 compared with DGLHD group.