Figure 6

DGLHD enhanced CD4+CD25+Foxp3+ Tregs differentiation in vivo.
(A) The percentage of CD4+CD25+Foxp3+ Tregs in spleen isolated from 12 week-old NOD mice treated with DGLHD for 4 weeks from 8 until 12 weeks of age or model control animals (n = 6). (B) Foxp3 mRNA expression in pancreas, spleen and thymus treated with DGLHD for 4 weeks were detected by qPCR. Data were presented as means ± SD (n = 3). *P < 0.05, **P < 0.01 compared with model control group.