Table 2 Effects of hepatitis C virus replication on MHC class I molecule expression.

From: Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression

 

MHC Class I Molecule Expression (MFI)

Reduction Rate of MHC Class I Molecule Expression (%)

HCV (+)

HCV (−)

TH/JFH1-RL

34.6 ± 1.0

42.0 ± 1.6

17.7 ± 0.7

TH/JFH1-RM

38.4 ± 1.0

43.7 ± 1.0

12.1 ± 1.2

TH/JFH1-QL

29.9 ± 2.0

43.9 ± 1.4

32.0 ± 2.5*

TH/JFH1-QM

31.0 ± 0.6

44.9 ± 1.1

30.8 ± 0.5*

  1. MFI, mean fluorescence intensity; MHC, major histocompatibility complex. *p < 0.05 compared with aa70R strains.
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