Table 2 Summary of the observations in the experiment 2.

From: Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model

Mouse no.a

Viral DNAb

Anemiac

NSE stainingd

Notes

BM

Spleen

Macrophagese

Phagocytosisf

9

–

–

–

+

+/−

 

10

+

+

+

++

+

Exhibited anemia and recovered.

11

+/−

+/−

–

+

–

 

12

+

+

+

NA

NA

Exhibited anemia and suddenly died.

13

+

+

–

+

+/−

 

14

+

+

–

+

–

 

15

+

+

–

+

–

 

16

–

–

–

–

–

 

17

–

–

–

+/−

–

 

18

–

–

–

–

–

 
  1. NA, not applicable because the BM fluid specimen was not obtained.
  2. aThe mouse numbers correspond with thos in Table 1 and Fig. 2.
  3. bThe results of PCR analyses (Fig. 2a) were summarized.
  4. cThe results of hematological analyses (Figs 2d,f,g) were summarized.
  5. dThe observation on NSE staining was assessed by the two hematologists (J.Y. and M.M.).
  6. emacrophages were : ++, frequently observed ; +, observed ; +/−, less observed ; −, not observed.
  7. fphagocytosing macrophages were : +, observed ; +/−, less observed ; −, not observed.
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