Figure 5
From: Role of Src in Vascular Hyperpermeability Induced by Advanced Glycation End Products
PP2 and knockout of RAGE prevents AGE-induced microvascular hyperpermeability.
(a,b) Wild type (WT) or RAGE−/− mice were pretreated with AGEs or AGEs plus PP2, The exudation of FITC-dextran from mesenteric venules was determined. Vascular permeability is expressed as the relative fluorescent intensity inside the vessel to that outside the vessel. n = 3, *P < 0.05 versus control group, #P < 0.05 versus AGEs. Each image was recorded at a 100 × magnification.
