Table 1 Candidate genes involved in hypoxia response showing selection in the eastern Himalayas great tits.
Pathways | Kegg map | Gene | Hypoxia response in other organisms | Reference |
|---|---|---|---|---|
MARK signaling pathway | Map 04010 | NFKB2 | Hypoxia-induced cell | |
MARK1 | Hypoxia-induced cell | |||
RPS6KA3 | ||||
PTPN5 | ||||
RPS6KA5 | ||||
PI3K-akt signaling pathway | Map 04151 | CREB1 | Hypoxia-induced cell | |
F2R | ||||
LAMB4 | ||||
LAMB1 | ||||
ITGA6 | Hypoxia-induced cell | |||
ITGA2 | Tibetan pig | |||
PI3KCG | Tibetan | |||
PRKAA1 | Andeans | |||
THBS4 | Hypoxia-induced mouse | |||
VWF | Hypoxia-induced cell | |||
mTOR signaling pathway | Map 04150 | PI3KCG | Tibetan | |
PRKAA1 | Andeans | |||
RPS6KA3 | ||||
Calcium signaling pathway | Map 04020 | CHRNA7 | ||
F2R | ||||
ITPR2 | Hypoxia-induced cell | |||
CAMK2G | ||||
HIF-1 signaling pathway | Map 04066 | EP300 | Hypoxia-induced cell | |
PI3KCG | Tibetan | |||
CAMK2G | ||||
MARK1 | Hypoxia-induced cell | |||
VEGF signaling pathway | Map 04370 | PI3KCG | Tibetan) | |
Other genes | ALOX5 | Human |
