Figure 8
From: Hofmeister effect of anions on calcium translocation by sarcoplasmic reticulum Ca2+-ATPase

Idealized scheme depicting the conformational change E1P → E2P in SERCA and the partial local perturbation of the membrane curvature.
The purple circles represent the Ca2+ ions that are translocated from the cytoplasm (top) to the sarcoplasmic reticulum (SR) lumen (bottom). For the conformational change of the enzyme see Figure 14 in ref. 18 and Fig. 1 in ref. 55.