Figure 3
From: Jagged-2 enhances immunomodulatory activity in adipose derived mesenchymal stem cells
Immunological analysis of AMSCs after 7 days of chondrogenic differentiation or 48 hours of IFN-γ pretreatment.
(A) FACS analysis for HLA expression in AMSCs following 7 days of chondrogenic differentiation or 48 hours of IFN-γ pretreatment. (B) AMSCs do not elicit a proliferative response from allogeneic lymphocytes after chondrogenic differentiation and/or IFN-γ pretreatment. (C) Inhibition of mitogen-stimulated lymphocyte proliferation by AMSCs increased after chondrogenic and/or IFN-γ pretreatment. (D) Suppression of mitogen-stimulated lymphocyte activity by AMSCs is retained after osteogenesis and/or IFN-γ pretreatment.
