Table 1 Characteristics of the SAPPHIRe Chinese participants.

From: Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population

Variables

Baseline

Follow-up

N

Mean ± SD

N

Mean ± SD

Age

1144

48.35 ± 9.09

759

53.18 ± 9.51

Gender (male, %)

537

46.94

348

45.85

BMI (kg/m2)

935

24.96 ± 3.43

678

25.46 ± 3.49

FPG (mmol/l)

1136

88.52 ± 10.62

671

95.98 ± 23.09

1 h-PG (mmol/l)

1040

166.45 ± 40.39

629

187.99 ± 49.58

2 h PG (mmol/l)

1023

127.98 ± 32.47

632

148.55 ± 52.03

FINS (pmol/l)

1133

7.37 ± 5.47

674

6.58 ± 5.41

1 h INS (pmol/l)

1039

77.26 ± 56.3

632

84.53 ± 66.83

2 h INS (pmol/l)

1042

61.5 ± 55.58

633

72.39 ± 66.75

HOMA-IR

1132

1.65 ± 1.35

669

1.63 ± 1.56

HOMA-beta

1112

117.76 ± 119.59

663

90.03 ± 144.45

AUCg (mmol*hr/l)

1014

296.4 ± 56.83

629

333.48 ± 82.34

AUCi (pmol*hr/l)

1031

111.88 ± 78.97

NA

NA

  1. BMI: body mass index, AUCg: area under curve of plasma glucose, FPG: fasting plasma glucose concentration, 1 h-PG: 1 hr plasma glucose concentration during OGTT, 2 h-PG: 2 hr plasma glucose concentration during OGTT, FINS: fasting plasma insulin concentration, 1 h-INS: 1 hr plasma insulin concentration during OGTT, 2 h-INS: 2 hr plasma insulin concentration during OGTT, AUCg: area under curve of plasma glucose, AUCi: Area under curve of plasma insulin.
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