Table 3 Family-based association test of PCSK2 haplotypes with various traits of glucose homeostasis in SAPPHIRe Chinese population according to additive model.

From: Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population

  1. All the traits were adjusted for age, gender and BMI.
  2. aHaplotype-specific P-value permutation test 10,000 times.
  3. bWhole marker permutation test (chisq sum) 10,000 times; FPG: Fasting plasma glucose concentration; 1 h-PG: 1 hr plasma glucose concentration during OGTT; 2 h-PG: 2 hr plasma glucose concentration during OGTT; FINS: fasting plasma insulin concentration; 1 h-INS: 1 hr plasma insulin concentration during OGTT; 2 h-INS: 2 hr plasma insulin concentration during OGTT; AUCg: area under curve of plasma glucose; AUCi: area under curve of plasma insulin; “–” Z-values unavailable due to sparseness.
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