Figure 2

Experiment design.
Time line representing the AIT schedule (bottom) and the different time points (basal, 1, 3, 6 and 12 months) in which patients were clinically evaluated and blood samples were taken. Blood samples were always obtained before AIT injection. All laboratory analysis were done in cryopreserved cells and frozen sera after the 12 months and before classification of the patients in RP and NRP.