Figure 4
Plasma-cells phenotyping.
Was done in cryopreserved cells after 1 year of AIT by flow cytometry. Box plots represent the median and IQR of the percentage of cells of each phenotype. Data is shown for CG, NRP and RP during 1-year follow-up of AIT. (A) Plasmablast (CD20+CD38+CD138+); (B) Plasma-cells (CD20−CD38+CD138+); Results for these cells were expressed as percentage of CD19+ cells. (B1) Long live Plasma-cells (CXCR4+); (B2) Inflammatory Plasma-cells (CXCR3+); these results were expressed as percentage of Plasma cells. A significant reduction of the percentage of inflammatory plasma-cells was observed during the AIT. Statistical Wilcoxon and Mann-Whitney U tests were performed. The Bonferroni correction was applied for comparison of three groups and five different time points.
